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We created GlucoZone for adults looking for a liquid supplement focused on blood sugar health. You get berberine HCl, turmeric root extract, green tea extract and black pepper extract together in one dropper bottle. It’s a simple way to add this four-ingredient blend to your daily supplement routine, with no capsules to swallow.

We chose berberine for our formula because of research into glucose metabolism—the way your body processes and uses blood sugar. Here are three findings that make berberine an ingredient of interest:

• Your cells’ energy system. In animal and cell experiments, berberine activated AMPK, an enzyme that helps regulate cellular energy use, and influenced processes that help glucose enter muscle cells.

  Read the AMPK study — Lee et al., 2006.

• Breaking down glucose. Another animal and cell study found that berberine increased glucose use and glycolysis—the process cells use to break down glucose.

  Read the glucose-metabolism study — Yin et al., 2008.

• Blood-sugar measurements. In a three-month trial involving 116 adults with type 2 diabetes and abnormal blood lipids, 1,000 mg of berberine daily improved fasting glucose, glucose after a glucose challenge, and HbA1c compared with placebo. HbA1c reflects average blood sugar over roughly three months.

  Read the human trial — Zhang et al., 2008.

You get a 940 mg blend in each 1 mL serving, combining:

• Berberine HCl
• Turmeric root extract
• Green tea extract
• Black pepper extract

Together, these four ingredients make up the 940 mg blend in your daily serving.

Our formula includes turmeric root extract. Within turmeric is a family of compounds called curcuminoids, including curcumin. Research on these compounds spans three areas of health:

• Blood sugar and insulin function. In a nine-month trial in adults with prediabetes, 1,500 mg of standardized curcuminoids daily improved blood-sugar measurements and measures of insulin function compared with placebo.

  Read the human trial — Chuengsamarn et al., 2012.

• Inflammation and antioxidant activity. In an eight-week trial in adults with metabolic syndrome, a daily combination of 1,000 mg curcuminoids and 10 mg piperine reduced C-reactive protein, a marker of inflammation, and improved certain measures of oxidative stress compared with placebo.

  Read the human trial — Panahi et al., 2015.

• Blood-vessel function. A 12-week trial in healthy middle-aged and older adults found improved function of the lining of blood vessels with a specially formulated curcumin supplement. Participants took 2,000 mg of the Longvida preparation daily, supplying approximately 400 mg of curcumin. The findings involved nitric oxide, which helps blood vessels widen, and reduced oxidative stress within the vessels.

  Read the human trial — Santos-Parker et al., 2017.

Green tea contains plant compounds called catechins, including EGCG. These compounds have attracted research interest for their effects on glucose metabolism and the use of fat as fuel.

One small research paper reported two short-term experiments in healthy young men. The researchers used a catechin-rich extract supplying approximately 890 mg of polyphenols, including 366 mg of EGCG, during the 24 hours before testing:

• Insulin sensitivity: The glucose-testing experiment, involving 11 men, found an improvement in a measure of insulin sensitivity.
• Fat use during exercise: The cycling experiment, involving 12 men, found increased fat oxidation—the use of fat as fuel—during moderate exercise.

Read the human experiments — Venables et al., 2008.

Black pepper contains piperine, a compound studied for its role in curcumin absorption.

In a human study, taking 20 mg of piperine with 2,000 mg of curcumin increased the amount of curcumin reaching the bloodstream compared with taking curcumin alone. This finding highlights piperine’s role in research on curcumin bioavailability—the amount that becomes available in the body after taking it.

Read the absorption study — Shoba et al., 1998.

Yes. In the three-month study involving 116 adults with type 2 diabetes and abnormal blood lipids, researchers also examined blood fats. Participants taking 1,000 mg of berberine daily had improvements in LDL cholesterol, total cholesterol and triglycerides compared with placebo.

Read the blood-lipid findings — Zhang et al., 2008.

You can open the research links in each answer to read the original paper or its published summary. You’ll find details about the ingredient preparation, the amount studied, the participants, the length of the study and the results.

For another perspective on the green tea research, you can also explore this 16-week study of a standardized green tea extract — Hsu et al., 2011.

Our formula also contains olive oil, D-limonene, ethyl alcohol and strawberry flavoring. The flavoring contains cane sugar, dextrose, fructose, strawberry, natural flavor and plant extractives. Check the complete ingredient list before you order, especially if you need to avoid a particular ingredient.

Shake the bottle very well before each use. Once a day, use the dropper to measure 1 mL, place it in your mouth, hold it there for 30 seconds, then swallow. GlucoZone is for adults. Read the directions and cautions before you begin.

You get 30 servings in each 30 mL bottle. Take one 1 mL serving a day, and one bottle gives you a 30-day supply.

GlucoZone delivers berberine in a liquid nanoparticle formulation. Measure your serving with the dropper, hold it in your mouth for 30 seconds, then swallow. You get berberine together with turmeric, green tea and black pepper extracts in one daily serving.

Researchers have also investigated sublingual delivery—placing a preparation under the tongue—as a way to improve berberine absorption. In a 2024 study in rats, a specially engineered berberine–albumin nanoparticle preparation produced higher blood levels when given sublingually than by the oral route. This is an encouraging finding in research on berberine delivery.

Read the sublingual-delivery animal study — Attia et al., 2024.

No. Take the recommended 1 mL serving once a day. Do not take extra or change your serving to try to speed up results.

Do not use GlucoZone if you take medication or have a medical condition, including diabetes. Do not stop or change your prescribed medication to take GlucoZone. Always consult your physician before taking a dietary, nutritional or herbal supplement.

No. Do not use GlucoZone if you are pregnant or nursing. GlucoZone is for adults. Do not give it to children, and keep the bottle out of their reach.

Upset stomach or other side effects are possible. Stop using GlucoZone immediately if you experience side effects, and contact your healthcare professional.

Yes. GlucoZone contains caffeine from our green tea extract. Your recommended serving is 1 mL once daily. The caffeine amount per serving has not yet been confirmed. If you need to limit or avoid caffeine, check with your healthcare professional before considering GlucoZone.

Yes. Our liquid formula contains ethyl alcohol. Your entire recommended daily serving is just 1 mL, and alcohol makes up only part of that serving.

We use strawberry flavoring in GlucoZone. Take your measured serving directly from the dropper as directed.

Some users report noticing improvements in as little as one week, while others report improvements after one or two months. Results vary from person to person.

Follow the recommended directions for 1 mL once daily and read the cautions before use. Do not increase your serving to try to speed up results. GlucoZone is not intended to diagnose, treat, cure or prevent any disease.

Your GlucoZone is made in the USA, exclusively for Austin Herbal Sciences.

Choose 1, 3, 6 or 12 bottles. Buy a larger package, and you pay less per bottle:

All prices are in US dollars. Per-bottle prices are rounded to the nearest cent and exclude shipping, handling and any applicable tax. The shipping charge shown above is for an order of one package.

For these combined orders, your shipping and handling charges are:

Two 3-bottle packages use the 6-bottle shipping rate, and two 6-bottle packages use the 12-bottle shipping rate. Two 12-bottle packages cost twice the 12-bottle shipping rate.

Keep your next bottle ready, pay less per bottle and reorder less often. If GlucoZone is part of your daily supplement routine, a larger package makes it easier to plan ahead.

With the 12-bottle package, you pay $51.15 per bottle, compared with $84.77 for the one-bottle package. You secure today’s package price for the bottles in this order. Future orders use the price available when you reorder. Shipping and handling are additional.